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A bee larva is deposited in the open brood cell. Egg laid by the queen 8 days after laying 9 days after laying 10 – 11 days after laying 12 – 20 days after laying 21 days after laying A fertilized female Varroa mite enters the cell 15 hours before it is capped. The cell is sealed with a wax cap and the fertilized Varroa mite is enclosed within the cell, where it feeds on haemolymph from the bee larva. The female mite lays an egg every 30 hours. The first offspring is a male; the subsequent offspring are all female. The female mite continues to lay eggs. As soon as the female offspring reach sexual maturity (in 5 to 6 days), they are fertilized by the one male mite in the cell. The young bee leaves the cell carrying two fertilized female mites. Immature mites and the male remain within the cell. The Varroa mite’s rapid rate of reproduction means that just a few female mites can produce many thousands of offspring during the course of a year. That’s why Apivar is so effective — it treats several successive generations of mites, instead of just one.