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Oxalic acid (OA) is a natural acaricide used for treatment against varroa mites in colonies with no/low brood, packages, or swarms.The label presents three different methods for treatment. The 35 gram pack will treat 20 colonies using the direct sprinkle method and 35 colonies with the use of the vaporizer. You must follow those directions exactly, for outdoor use only. Oxalic acid applications are and should be used only in late fall or early spring when little or no brood is present.